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Appendix — Claude Code MCP server: features and setup

Appendix searches medical literature and treatment guidance, then sends clinical encounters to a physician for review. A prescription may be provided if needed.

Install into Claude Code · Platform CLI: remote server All methods and platforms ↓
claude mcp add --transport http appendix https://mcp.appendix.com/mcp
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What Appendix does

Appendix gives an agent tools to search medical references, submit a clinical letter for physician review, and view available conditions and medications. search_knowledge_base looks up literature and treatment guidance. submit_encounter sends an encounter for review, while list_conditions returns available conditions and medications.

The server uses Streamable HTTP transport. In Claude Code, connect it with claude mcp add --transport http appendix https://mcp.appendix.com/mcp. A physician reviews submitted encounters; the agent does not approve them or issue prescriptions itself.

What it helps with

  • search medical literature and treatment guidance
  • send a clinical letter for physician review
  • check which conditions and medications are available

Example prompts for the agent

  • Search medical literature and treatment guidance for this condition.
  • Send this clinical letter to a physician for review.
  • Show the available conditions and medications.

How to install Appendix

Platform CLI: remote server

claude mcp add --transport http appendix https://mcp.appendix.com/mcp

Step by step, with commands for each platform: How to add an MCP server to Claude Code, Codex, Cursor, VS Code, Gemini CLI and more

Questions about Appendix

How do I install Appendix in Claude Code?

Run claude mcp add --transport http appendix https://mcp.appendix.com/mcp to connect the server over HTTP.

What does Appendix do?

It lets an agent search medical literature, submit clinical encounters for physician review, and look up available conditions and medications. A prescription may be issued if needed.

Which transport does Appendix use?

Appendix supports Streamable HTTP transport only, so the MCP client needs to support that transport.

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