reactome-skill — Codex skill: what it does, how to install
Queries Reactome ContentService for biological pathways, reactions, and participants. Returns concise markdown summaries directly in Codex.
npx skills add openai/plugins --skill reactome-skill -a codexWhat reactome-skill does
This skill queries the Reactome ContentService using an internal helper script scripts/rest_request.py. It passes a JSON payload via standard input to fetch pathway memberships, entity lookups, and diagram data. The agent outputs a short markdown summary instead of unparsed payloads.
Python must be installed locally to execute the script. The tool can limit list sizes with max_items=10 and save complete unformatted API outputs using the save_raw parameter. The raw payload path is reported back if exported.
Install this skill if your workflow involves querying biological databases during development. Skip it if you do not handle molecular pathway data.
What it helps with
- fetch biological pathway summaries by event identifier
- list molecular participants for a reaction
- save complete Reactome endpoint responses directly to disk
Example prompts for the agent
- Look up participants for event R-HSA-199420 in Reactome
- Find low-level pathways for entity P38398 in Homo sapiens
How to install reactome-skill
1Skills CLI (Vercel)
npx skills add openai/plugins --skill reactome-skill -a codex2Manually: put the files in place
.agents/skills/reactome-skill/SKILL.mdFor all projects use ~/.agents/skills/
1Skills CLI (Vercel)
npx skills add openai/plugins --skill reactome-skill -a claude-code2Manually: put the files in place
~/.claude/skills/reactome-skill/SKILL.mdCopy the whole skill folder; for one project use .claude/skills/reactome-skill/
Manually: put the files in place
.cursor/skills/reactome-skill/SKILL.mdCursor also reads .agents/skills/ and .claude/skills/
1GitHub CLI
gh skill install openai/plugins reactome-skill2Manually: put the files in place
.github/skills/reactome-skill/SKILL.mdPlatform CLI
gemini skills install https://github.com/openai/plugins --path plugins/life-science-research/skills/reactome-skillManually: put the files in place
.devin/skills/reactome-skill/SKILL.mdThe legacy .windsurf/skills/ path still works
Claude.ai
Zip the folder and upload it in Settings → Capabilities → Skills
From the same set201
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Questions about reactome-skill
How to install reactome-skill in Codex?
Run npx skills add openai/plugins --skill reactome-skill in your terminal.
What does reactome-skill do?
It queries the Reactome ContentService to retrieve concise pathway and molecular participant summaries.
What are the runtime requirements?
It requires a working Python installation to execute scripts/rest_request.py.