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chembl-skill — Codex skill for ChEMBL: use and install

This skill queries the ChEMBL API for activity, molecule, target, mechanism, and text-search data. Use it when you need concise summaries of ChEMBL records.

Install into Codex · Skills CLI (Vercel) All methods and platforms ↓
npx skills add openai/plugins --skill chembl-skill -a codex
Open on GitHub

What chembl-skill does

The skill sends requests through scripts/rest_request.py. It covers activity, molecule, target, and mechanism data, plus text search. By default, the agent turns the script's JSON response into a concise Markdown summary; it returns the JSON verbatim only when asked.

For activity, mechanism, and text-search collections, requests start with limit=10 and max_items=10. Search for a molecule with a query such as imatinib, or look up a specific record using an identifier such as CHEMBL25. In a long conversation, the agent runs requests again instead of relying on older results.

The script requires Python and uses the ChEMBL API. Install this skill when you need concise ChEMBL data summaries; it does not serve tasks outside that API.

What it helps with

  • find molecules with a text query
  • retrieve activity data for a molecule
  • look up a ChEMBL target
  • check a molecule's mechanism of action

Example prompts for the agent

  • Search ChEMBL for molecules matching imatinib and summarize the results.
  • Show the activity records for CHEMBL25.
  • Find the mechanism for CHEMBL25 and give me a short summary.

How to install chembl-skill

1Skills CLI (Vercel)

npx skills add openai/plugins --skill chembl-skill -a codex

2Manually: put the files in place

.agents/skills/chembl-skill/SKILL.md

For all projects use ~/.agents/skills/

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Questions about chembl-skill

How do I install chembl-skill in Codex?

Run npx skills add openai/plugins --skill chembl-skill -a codex. The skill file is placed at .agents/skills/chembl-skill/SKILL.md.

What does chembl-skill do?

It queries the ChEMBL API for activity, molecules, targets, mechanisms, and text-search results. The agent returns a concise summary by default.

What does chembl-skill need to run?

It uses Python to run scripts/rest_request.py, which sends requests to the ChEMBL API. Activity, mechanism, and text-search collections use limit=10 and max_items=10.

See also

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