# PhysiCell Configuration Builder

This MCP server lets an agent create, inspect, and export PhysiCell and PhysiBoSS model configuration files when those files need to be prepared or checked.

- MCP server · `type=mcp` · Claude Code, Codex, Cursor, GitHub Copilot, Windsurf (Devin Desktop), Cline, Zed, Gemini CLI · ★ 20
- Author: marcorusc
- License: GPL-3.0 · policy=link-only · description only; the file stays with the author
- Source: https://github.com/marcorusc/mcp-biomodelling-servers/tree/HEAD/physicell
- Updated: 2026-10-22
- HTML: https://affpapa.org/en/nevibecode/mcp/physicell-configuration-builder

## What it does

PhysiCell Configuration Builder exposes configuration work through MCP over stdio. An agent can use it to create settings for PhysiCell and PhysiBoSS, examine existing configuration content, and produce exported files for the model workflow.

It is shipped inside `mcp-biomodelling-servers`. Installing the package with `pip` or `uvx` also installs its modelling dependencies and the MCP Python SDK 2.x. The supported Python range is 3.10–3.15.

A `uv` installation is required when the server is started through `uvx`. The server can be connected to Claude Code, Codex, Cursor, GitHub Copilot, Windsurf (Devin Desktop), Cline, Zed, or Gemini CLI.

## Requirements
- Needs: Python and uv (commands run via uvx)

## Install

### Claude Code (native platform)

**Platform CLI**
```bash
claude mcp add physicell -- uvx mcp-biomodelling-servers
```
uvx runs the command named after the package; if the README names another one, use uvx --from mcp-biomodelling-servers <command>

### Codex

**Platform CLI**
```bash
codex mcp add physicell -- uvx mcp-biomodelling-servers
```
uvx runs the command named after the package; if the README names another one, use uvx --from mcp-biomodelling-servers <command>

### Cursor

**Config file**
File `.cursor/mcp.json`:
```json
{
    "mcpServers": {
        "physicell": {
            "command": "uvx",
            "args": [
                "mcp-biomodelling-servers"
            ]
        }
    }
}
```
uvx runs the command named after the package; if the README names another one, use uvx --from mcp-biomodelling-servers <command>

### GitHub Copilot

**Config file**
File `.vscode/mcp.json`:
```json
{
    "servers": {
        "physicell": {
            "type": "stdio",
            "command": "uvx",
            "args": [
                "mcp-biomodelling-servers"
            ]
        }
    }
}
```
uvx runs the command named after the package; if the README names another one, use uvx --from mcp-biomodelling-servers <command>

### Gemini CLI

**Platform CLI**
```bash
gemini mcp add physicell uvx mcp-biomodelling-servers
```
uvx runs the command named after the package; if the README names another one, use uvx --from mcp-biomodelling-servers <command>

## When to use it
- create a PhysiCell model configuration
- inspect PhysiBoSS settings
- export a completed configuration file
- prepare model parameters for an agent workflow

## Example prompts
- Create a PhysiCell configuration for this model.
- Inspect the PhysiBoSS settings and point out configuration problems.
- Export the completed PhysiCell configuration.

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From the same set: [marcorusc/mcp-biomodelling-servers](https://affpapa.org/en/nevibecode/by/marcorusc/mcp-biomodelling-servers.md) — 4 cards

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